These supplements target the root drivers of chronic inflammation including immune overactivation, oxidative stress, gut imbalance, hormonal inflammation, joint degeneration, and metabolic inflammation. Together, they support whole-body healing and long-term disease prevention.
1. Omega-3 Fatty Acids
Omega-3 Fatty Acids lower systemic inflammation, protect joints, reduce cytokine activity, and support brain and heart inflammation pathways.
When to take: Morning or midday with a fat-containing meal.
Best for joint pain, autoimmune flares, skin inflammation, brain fog, and cardiovascular inflammation.
2. Turmeric (Curcumin)
Turmeric blocks multiple inflammatory pathways and reduces pain, swelling, and oxidative tissue damage.
When to take: Morning or midday with food and black pepper for absorption.
Best for arthritis, muscle pain, digestive inflammation, skin flare-ups, and metabolic inflammation.
3. Black Seed (Nigella Sativa)
Black Seed Oil modulates immune response, reduces inflammatory antibodies, and supports inflammatory balance across multiple body systems.
When to take: Morning or evening with food.
Best for autoimmune inflammation, allergies, asthma, gut inflammation, and immune dysregulation.
4. Magnesium
Magnesium reduces stress-driven inflammation by calming the nervous system and lowering inflammatory cortisol signaling.
When to take: Evening or before bed.
Best for inflammation linked to stress, muscle tension, migraines, and sleep-related inflammation.
5. Vitamin D
Vitamin D regulates immune activity and suppresses autoimmune-driven inflammatory responses.
When to take: Morning with a fat-containing meal.
Best for autoimmune inflammation, frequent infections, bone inflammation, and low mood with inflammation.
6. Zinc
Zinc supports inflammatory enzyme regulation, tissue repair, and immune balance.
When to take: Midday or evening with food.
Best for skin inflammation, acne, slow wound healing, gut inflammation, and immune overactivation.
7. Probiotics
Probiotics regulate gut-driven inflammation, immune signaling, estrogen recycling, and brain-gut inflammatory pathways.
When to take: Morning on an empty stomach or before bed.
Best for bloating, IBS, food sensitivities, hormone-driven inflammation, and inflammatory skin conditions.
8. Coenzyme Q10
Coenzyme Q10 protects cells from inflammatory oxidative damage and supports mitochondrial repair.
When to take: Morning with a fat-containing meal.
Best for cardiovascular inflammation, statin-related inflammation, fatigue-linked inflammation, and aging-related inflammation.
9. Vitamin C
Vitamin C neutralizes inflammatory free radicals and supports tissue repair during inflammatory stress.
When to take: Morning or split throughout the day.
Best for skin inflammation, joint irritation, immune-driven inflammation, and slow healing.
10. Selenium
Selenium strengthens antioxidant enzymes that shut down inflammatory damage at the cellular level.
When to take: Morning with food.
Best for thyroid inflammation, autoimmune activity, premature aging, and chronic oxidative stress.
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